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Hit2Lead

From Hit to Lead at the Speed of Light

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Active aliphatic halides

methyl 4-(chloromethyl)-5-methyl-3-isoxazolecarboxylate5-(chloromethyl)-2-methylpyrazolo[1,5-a]pyrimidin-7(4H)-one1-benzyl-3-(chloromethyl)pyrrolidine hydrochloride2-(chloromethyl)-9-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one3-(bromomethyl)-1-methylpiperidine hydrobromide2-(chloromethyl)-1-methylpyrrolidine hydrochloride4-benzyl-2-(chloromethyl)-1,4-oxazepane1-benzyl-3-(chloromethyl)piperidine hydrochloride4-bromo-1,1,2,2-tetrafluorobutane1-bromo-5-fluoropentane2-(2-chloroethyl)-1-methyl-1H-imidazole hydrochloride4-(chloromethyl)-5-methyl-1,3-thiazole hydrochloride5-(chloromethyl)-3-methyl-1H-1,2,4-triazole hydrochloride5-(chloromethyl)-1,3-dimethyl-1H-1,2,4-triazole5-(2-bromoethyl)-3-methyl-2,4(1H,3H)-pyrimidinedione4-(bromomethyl)-1,3,5-trimethyl-1H-pyrazole hydrobromide3-(chloromethyl)-5-ethyl-1H-1,2,4-triazole hydrochloride4-(chloromethyl)-2,5-dimethyl-1,3-thiazole hydrochloride2-(chloromethyl)-3-methylquinoxaline5-(chloromethyl)-3-(trifluoromethyl)-1,2,4-oxadiazole3-(2-bromoethyl)tetrahydrothiophene 1,1-dioxide3-(bromomethyl)-1-ethylpyrrolidine hydrobromide2-(chloromethyl)-1-ethylpyrrolidine hydrochloride3-(bromomethyl)-1-methylpyrrolidine hydrobromide2-(chloromethyl)[1,2,4]triazolo[1,5-a]pyrimidine4-(chloromethyl)-1-methylpiperidine hydrochloride2-(bromomethyl)-1,3-thiazole hydrobromide2-(chloromethyl)-1-(methoxymethyl)-1H-imidazole hydrochloride2-(bromomethyl)-1-methylpiperidine hydrobromide3-(bromomethyl)-1-isopropylpyrrolidine hydrobromidetert-butyl 4-(bromoacetyl)-1-piperazinecarboxylate2-(chloromethyl)-1-cyclopropyl-1H-imidazole hydrochloride2-bromo-N,N-dimethylbutanamide1-(2-bromoethyl)-1H-benzimidazole hydrobromide2-(bromomethyl)-1-methyl-1H-benzimidazole hydrobromide3-(chloromethyl)-4-isopropyl-4H-1,2,4-triazole hydrochloride2-(chloromethyl)-4,5-dimethyl-1H-imidazole hydrochloride3-iodotetrahydrothiophene 1,1-dioxide3-(chloromethyl)-1-ethyl-1H-pyrazole hydrochloride5-(chloromethyl)-1-methyl-1H-pyrazole hydrochloride3-(chloromethyl)-4-ethyl-4H-1,2,4-triazole3-(chloromethyl)-4-methyl-4H-1,2,4-triazole hydrochloride4-(chloromethyl)-1,3-dimethyl-1H-pyrazole hydrochloride6-chloro-N-methyl-2-pyridinecarboxamide3-bromo-1-methyl-2-pyrrolidinone3-(bromomethyl)-1,2,4-oxadiazole4-(2-bromoethyl)-3-methyl-4H-1,2,4-triazole hydrobromide5-chloro-1,3-dimethyl-1H-1,2,4-triazoletert-butyl 3-(bromomethyl)-1-piperidinecarboxylate3-(bromomethyl)-5-methyl-1,2,4-oxadiazole3-chloro-1,5-dimethyl-1H-1,2,4-triazole3-(bromomethyl)-5-(trifluoromethyl)-1,2,4-oxadiazole4,6-dichloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine2-(2-chloroethyl)-1H-imidazole hydrochloride5-chloro-1-methyl-1H-1,2,4-triazole3-chloro-1-methyl-1H-1,2,4-triazole3-(bromomethyl)-4-methyl-1,2,5-oxadiazole4-(2-bromoethyl)-4H-1,2,4-triazole hydrobromide3-(bromomethyl)-5-ethyl-1,2,4-oxadiazoletert-butyl [(2-chloro-3-pyridinyl)methyl]carbamate4-bromotetrahydro-2H-thiopyran3-(bromomethyl)-5-isopropyl-1,2,4-oxadiazole3-(bromomethyl)tetrahydro-2H-pyran4-(chloromethyl)-2-methylpyridine hydrochloride2-bromo-1-cyclopropylethanol4-chloro-2-methyl-2-butanol3-(chloromethyl)-2-methylpyridine hydrochloride2-(3-bromopropyl)furan2-bromo-1-phenylethanol2-(chloromethyl)isonicotinonitrile hydrochloride2-(bromomethyl)-1,3,3-trimethylcyclohexenerac-(1R,2S,4S)-2-(bromomethyl)-7-oxabicyclo[2.2.1]heptane(1R)-2-bromo-1-phenylethanol3-(2-bromoethyl)pyridine hydrobromide5-(chloromethyl)-1-methyl-1H-1,2,4-triazole hydrochloride2-(bromomethyl)-3-methylpyridine hydrobromide5-(bromomethyl)-1-methyl-2-piperidinone5-(chloromethyl)-4-methyl-2-(trifluoromethyl)pyrimidine(1S)-2-bromo-1-phenylethanol2-(2-bromoethyl)-1,4-dioxanerac-(1R,2R,4S)-2-(bromomethyl)-7-oxabicyclo[2.2.1]heptane4-(bromomethyl)-1-methyl-2-pyrrolidinone5-(bromomethyl)-1-isopropyl-2-piperidinone4-(bromomethyl)-2-pyrrolidinone5-(bromomethyl)-4-methyl-1,3-thiazole hydrobromide5-bromo-1-pentyne2-(chloromethyl)-5-methylpyrazine hydrochloride4-(bromomethyl)-1,1-difluorocyclohexanetrans-4-bromotetrahydro-3-thiopheneol 1,1-dioxide5-(bromomethyl)dihydro-2(3H)-furanone3-(chloromethyl)-5-isobutylisoxazole2-(bromomethyl)-4,5-dimethyl-1,3-thiazole hydrobromide2-(chloromethyl)-6-methylpyridine hydrochloride2-(chloromethyl)-6-methyl-1H-benzimidazole1-benzyl-5-(chloromethyl)-1H-imidazole hydrochloride2-(chloromethyl)-4-methoxypyridine2-(chloromethyl)-1-methylpiperidine5-(chloromethyl)-1-isopropyl-1H-imidazole3-chloro-N-3-pyridinylpropanamide2-(chloromethyl)-8-methylimidazo[1,2-a]pyridine