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Hit2Lead

From Hit to Lead at the Speed of Light

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Active aliphatic halides

2-chloro-N-1,3-thiazol-2-ylpropanamide2-chloro-N-cyclopentylpropanamide6-(chloromethyl)-1-methyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one2-chloro-N-(1,3-dimethyl-1H-pyrazol-4-yl)acetamide2-chloro-N-1,3,4-thiadiazol-2-ylpropanamide2-(2-bromoethyl)-6-methylpyridine hydrobromide2-(chloromethyl)thieno[3,2-d]pyrimidin-4(3H)-one2-(bromomethyl)imidazo[1,2-a]pyrimidine hydrobromide5-(chloromethyl)-4-isopropyl-1,2,3-thiadiazole2-chloro-N-isobutylpropanamide5-(chloromethyl)-3-ethylisoxazole2-chloro-N-methylacetamide3-(chloromethyl)-5-cyclopropylisoxazole1-(2-chloropropanoyl)azepane2-chloro-N-(4,5-dihydro-1,3-thiazol-2-yl)propanamide2-chloro-N-(1,5-dimethyl-1H-pyrazol-4-yl)acetamide1-(chloroacetyl)-4-methylpiperazine hydrochloride2-chloro-N-(1-methyl-1H-pyrazol-3-yl)acetamide3-chloro-N-isopropylpropanamide3-(chloromethyl)-N-methyl-1,2,4-oxadiazole-5-carboxamide3-bromotetrahydro-2H-pyran5-(chloromethyl)-3-cyclopropyl-1,2,4-oxadiazole5-(chloromethyl)-3-isopropylisoxazole3-(chloromethyl)-N,N-dimethyl-1,2,4-oxadiazole-5-carboxamide3-(chloromethyl)-5-(2-furyl)-1,2,4-oxadiazole5-(chloromethyl)-N-methyl-2-furamide1-(2-chloro-1-methylethyl)pyrrolidine hydrochloride2-(chloromethyl)-1-isopropyl-1H-imidazole(3-chloropropyl)ethyl(methyl)amine hydrochloride2-chloro-1-(3,4-dimethylphenyl)ethanone5-(chloromethyl)-3-methyl-1,2,4-oxadiazole4-(chloromethyl)-N-methylbenzamide1-(3-chloropropyl)-4-methyl-1H-pyrazole hydrochloride1-(2-chloro-1-methylethyl)-1H-1,2,4-triazole hydrochloride2-(chloromethyl)-4,5-dimethyl-1,3-thiazole2-chloro-1-(2,5-dimethylphenyl)ethanone4-(2-chloro-1-methylethyl)morpholine5-(chloromethyl)-3-(2-methoxyethyl)-1,2,4-oxadiazole5-(chloromethyl)-1,2,4-oxadiazole-3-carboxamide5-(chloromethyl)-4-ethyl-2-methyl-1,3-thiazole1-chloro-N,N-dimethylmethanesulfonamide2-(chloromethyl)-3,5-dimethyl-4(1H)-pyridinone hydrochloride2-(chloromethyl)-1-methylpiperidine hydrochloride3-(chloromethyl)-1,2,4-oxadiazole-5-carboxamide7-(chloromethyl)-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one2-chloro-N-(1-methyl-1H-pyrazol-4-yl)acetamide5-(chloromethyl)-N,N-dimethyl-2-furamide1-[(chloromethyl)sulfonyl]pyrrolidine5-(chloromethyl)-N-methyl-1,2,4-oxadiazole-3-carboxamide4-(chloromethyl)-2-methyl-1,3-thiazole hydrochloride4-chlorotetrahydro-2H-pyran3-(bromomethyl)pyridine hydrobromide4-(chloromethyl)-1,3-thiazole hydrochloride1-(3-chloropropyl)-1H-tetrazole4-(chloromethyl)-N-methyl-1,3-thiazol-2-amine hydrochloride5-(chloromethyl)-2-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-ol7-chloro-2-(chloromethyl)-4H-pyrido[1,2-a]pyrimidin-4-one1-(3-chloropropyl)-5-methyl-1H-tetrazole5-(chloromethyl)dihydro-2(3H)-furanone1-(2-bromoethyl)-2-pyrrolidinone3-chloro-N,N-dimethyl-1-propanesulfonamide(2S)-2-(chloromethyl)-1-ethylpyrrolidine4-(chloromethyl)-2-thiophenecarbaldehyde1-(2-bromoethyl)-2-methyl-1H-imidazole hydrobromidemethyl 5-(bromomethyl)-2-thiophenecarboxylate2-(chloromethyl)-5-(2-furyl)-1,3,4-oxadiazole4-(chloromethyl)benzamide2-(chloromethyl)-4H-pyrido[1,2-a]pyrimidin-4-one2-(chloromethyl)-6-methyl-4H-pyrido[1,2-a]pyrimidin-4-one2-(chloromethyl)-9-methyl-4H-pyrido[1,2-a]pyrimidin-4-one1-(3-bromopropyl)-1H-imidazole hydrobromide3-(chloromethyl)-1-methyl-2(1H)-quinolinone1-chloro-2-(methylsulfonyl)ethane2-(chloromethyl)-3-methylpyrazine hydrochloride3-(chloromethyl)-4,5-dimethyl-4H-1,2,4-triazole hydrochloride2-(chloromethyl)-3-methoxypyridine hydrochloride2-chloro-6-(chloromethyl)pyridineN-(1-benzylpiperidin-4-yl)-2-bromoacetamide2-bromo-N-(2-pyridinylmethyl)acetamide hydrochloridetert-butyl 4-iodopiperidine-1-carboxylatecis-4-(chloroacetyl)-2,6-dimethylmorpholine2-(chloromethyl)-5-methoxy-4H-pyran-4-one6-(chloromethyl)-1H-pyrrolo[2,3-b]pyridine3-(bromomethyl)tetrahydro-2H-thiopyran 1,1-dioxide3-(bromomethyl)tetrahydrofuran2-(chloromethyl)-5-methoxy-4-pyridinol6-(bromomethyl)-1,4-dioxepane2-(2-bromoethyl)-1,1-difluorocyclopropane3-(chloromethyl)-2-methoxypyridine4-(chloromethyl)-2-methyl-1,3-oxazole2-(bromomethyl)-1,1-difluorocyclopropane6-chloro-N,N-dimethyl-2-pyridinecarboxamide3-(2-bromoethyl)tetrahydrofuran1-benzyl-2-(chloromethyl)-1H-imidazole hydrochloride5-(chloromethyl)-1-cyclopropyl-1H-imidazole hydrochloride4-(bromomethyl)-1-methylpiperidine hydrobromide7-(chloromethyl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one(2R)-1-benzyl-2-(chloromethyl)pyrrolidine hydrochloride1-benzyl-4-(chloromethyl)piperidine hydrochloride2-(bromomethyl)-1-methyl-1H-imidazole hydrobromide