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Hit2Lead

From Hit to Lead at the Speed of Light

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(5E)-5-heptenoic acid3-[(2R)-5-oxo-2-pyrrolidinyl]propanoic acidethyl (2E)-4-methyl-2,4-pentadienoate1-methyl-1H-pyrazolo[4,3-b]pyridine-6-carboxylic acid2-bromo-3-(methylthio)pyridine4-chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazolerac-(4aS,7aS)-hexahydropyrrolo[3,4-b][1,4]oxazin-3(2H)-onetrans-5-aminocyclooctanol hydrochloridetrans-3-(4-pyridinyl)cyclobutanamine dihydrochloride5-(4-piperidinylmethyl)-2(1H)-pyridinone dihydrochloride2-cyclopropyl-2,6-diazaspiro[3.3]heptane bis(trifluoroacetate)2-cyclohexen-1-amine3-hydroxy-2-methylisonicotinonitrilemethyl (2S)-4-methyl-5-oxo-2-piperazinecarboxylate hydrochloridetert-butyl rac-(5aS,8aS)-3-aminohexahydro-2H,7H-[1,4]dioxepino[2,3-c]pyrrole-7-carboxylaterac-(6R,8aS)-octahydro-6-indolizinol hydrochloride5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-6-ol3-bromo-4-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine8-(tert-butoxycarbonyl)-2,8-diazaspiro[4.5]decane-3-carboxylic acid hydrochloridecis-3-(benzyloxy)cyclobutanamine hydrochloridetert-butyl cis-4-amino-3-methyl-1-piperidinecarboxylate hydrochloride5-bromoimidazo[1,2-a]pyrazine3-[(methylsulfonyl)methyl]pyrrolidine hydrochloride4-penten-1-amine[trans-4-methoxy-1,1-dioxidotetrahydro-3-thienyl]amine hydrochloriderac-(2S,4S)-2-cyclopropyl-4-piperidinol hydrochloride4-(3-pyrrolidinyl)-1H-imidazole dihydrochloride5-iodoisothiazole5-(bromomethyl)-1-isopropyl-2-piperidinonerac-[(3aS,6aS)-2-methylhexahydropyrrolo[3,4-c]pyrrol-3a(1H)-yl]methanol dihydrochloride1-(tetrahydro-2-furanyl)ethanone5-methylpyrazolo[1,5-a]pyridine-2-carboxylic acid2-acetyl-1,3-thiazole-5-carboxylic acid1-(4-piperidinyl)methanesulfonamide hydrochloriderac-(3'R,4'R)-1,3'-bipyrrolidin-4'-ol dihydrochloride5-methylpyrazolo[1,5-a]pyridin-3-amine{[(2S)-1-methyl-2-pyrrolidinyl]methyl}amine dihydrochloride4-(bromomethyl)-2-pyrrolidinone2-oxo-2H-pyran-5-carbonitrile1-isopropyl-D-proline hydrochloride(2R)-2-ethyl-1-methylpiperazine dihydrochloriderac-(8R,8aS)-8-aminohexahydro-5(1H)-indolizinonerac-(3aR,6aR)-hexahydro-2H-furo[3,2-b]pyrrole hydrochloride(5s,8r)-1-azaspiro[4.5]decan-8-ol hydrochlorideN~2~-methyl-D-alaninamide hydrochloride3-bromo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine5-bromo-3-cyclopropyl-1-methyl-1H-pyrazole4-methyl-1-oxa-4,9-diazaspiro[5.5]undecane dihydrochloride5-methyl-4-isoxazolecarbonitriletert-butyl 6-oxa-2,9-diazaspiro[4.5]decane-9-carboxylate hydrochloride(2S)-4-methyl-5-oxo-2-piperazinecarboxylic acid hydrochloride(2S)-1-(1-piperazinyl)-2-propanol dihydrochloride3-methoxy-2-methyl-4-pyridinamine2-(1-aminoethyl)-1,3-thiazole-5-carboxylic acid hydrochloridecis-3-(4-pyridinyl)cyclobutanamine dihydrochloridetrans-1-(tert-butoxycarbonyl)-3-methyl-2-pyrrolidinecarboxylic acid{[(2R)-1-isopropyl-2-pyrrolidinyl]methyl}amine dihydrochloride4-bromo-1,3-dihydro-2-benzofuran[cis-4-methoxytetrahydro-3-furanyl]amine hydrochloride(3,5-dimethyl-1H-pyrazol-4-yl)boronic acid(4,4-difluorocyclohexyl)methanolN~2~-methyl-L-alaninamide hydrochloriderac-(1S,2R,4R)-bicyclo[2.2.1]hept-2-ylamine hydrochloride1-benzofuran-6-ylboronic acid5-(hydroxymethyl)-2-pyrazinecarboxylic acid1-propionyl-D-proline4-methyl-2-morpholinecarboxylic acid hydrochloride1-D-prolylpiperidine4-bromo-2,3-dichlorophenolrac-(3R,4R)-4-methoxy-1-methyl-3-pyrrolidinamine dihydrochloridecis-3-(2-aminoethyl)cyclobutanol hydrochloriderac-(1S,2S,4R)-6-oxo-7-oxabicyclo[2.2.1]heptane-2-carboxylic acid(3R,8aS)-3-methylhexahydropyrrolo[1,2-a]pyrazin-4(1H)-one hydrochloridetert-butyl rac-(3R,4R)-4-amino-3-ethyl-1-piperidinecarboxylate hydrochloride4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-naphthol4-[(2R)-2-pyrrolidinylmethyl]morpholine9-methyl-1-oxa-9-azaspiro[5.5]undecan-4-amine dihydrochloridepyrazolo[1,5-a]pyridine-4-carboxylic acidrac-(1S,5S,8R)-3-(tert-butoxycarbonyl)-8-hydroxy-3-azabicyclo[3.2.1]octane-1-carboxylic acid3-(1H-tetrazol-1-yl)-1-propanamine2-(6-amino-2-pyridinyl)ethanolrac-(2R,4S)-2-ethyl-4-piperidinol hydrochloride6-oxa-2,9-diazaspiro[4.5]decan-8-one hydrochloride(1-hydroxy-5,6,7,8-tetrahydro-2-naphthalenyl)boronic acidtert-butyl rac-(3R,4R)-3-amino-4-methoxy-1-pyrrolidinecarboxylate hydrochloride6-(aminomethyl)-4-methyl-3-morpholinone hydrochloride2-bromo-4-fluoro-5-(trifluoromethyl)phenoltert-butyl (3-endo)-3-amino-9-azabicyclo[3.3.1]nonane-9-carboxylate hydrochloride2-(2H-tetrazol-5-yl)morpholine hydrochlorideN,N-dimethyl-D-alanine hydrochloride(2S)-2-hydroxy-2-phenylethanimidamidetert-butyl [2-(3-morpholinyl)ethyl]carbamate hydrochloridetrans-1,2-dimethyl-4-piperidinamine dihydrochloride(4-methyl-2-pyridinyl)acetic acid hydrochloridetrans-3-(3-pyridinyl)cyclobutanamine dihydrochloridetert-butyl rac-(3aR,6aS)-4-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylatetrans-3-hydroxycyclobutanecarboxylic acidtert-butyl cis-4-amino-2-methyl-1-piperidinecarboxylate hydrochloride4-cyclohexyl-2-pyrrolidinone5-hydroxy-1-methyl-2-piperidinone