Bioactive Small Molecules

1-(4-fluorobenzyl)-1H-benzimidazole

Compound 12

Compound 12 (click to show)
Compound 12 (click to hide)
Title:
Discovery of a Novel and Potent Class of F. tularensis Enoyl-Reductase (FabI) Inhibitors by Molecular Shape and Electrostatic Matching
Reference:
J Med Chem. 2012 Jan 12;55(1):268-79. doi: 10.1021/jm201168g. Epub 2011 Dec 5.
Authors:
Kirk E. Hevener, Shahila Mehboob, Pin-Chih Su, Kent Truong, Teuta Boci, Jiangping Deng, Mahmood Ghassemi, James L. Cook, and Michael E. Johnson
Compounds:
Compound 4(5269765), Compound 5 (7996488), Compound 6 (5571325), Compound 7(6750659), Compound 8(7699754), Compound 9(7725253), Compound 11(5542661), Compound 12(7355451), Compound 13(9075115), Compound 14(5125538), Compound 15(5660856), Compound 16(6130731)