Bioactive Small Molecules

N-(2-methoxyphenyl)-N'-2-naphthylurea

BLT-4, INF 271, INF271

BLT-4 (click to show)
BLT-4 (click to hide)
Title:
Role of macrophage activation in the lipid metabolism of postprandial triacylglycerol-rich lipoproteins
Reference:
Experimental Biology and Medicine, 2013 Jan;238(1):98-110
Authors:
Mariarosaria Napolitano, Simona Sennato, Kathleen M Botham, Federico Bordi and Elena Bravo
Compounds:
BLT-1 (5234221), BLT-4 (5109586)
INF 271 (click to show)
INF 271 (click to hide)
Title:
Multiple Novel Inhibitors of the NorA Multidrug Transporter of Staphylococcus aureus
Reference:
Antimicrobial Agents and Chemotherapy 1999 Oct;43(10):2404-8
Authors:
Penelope N. Markham, Eric Westhaus, Katya Klyachko, Michael E. Johnson, and Alex A. Neyfakh
Compounds:
INF 55 (5107950), INF 240 (5187143), INF 271 (5109586), INF 277 (5213684), INF 392 (5241292)
BLT-4 (click to show)
BLT-4 (click to hide)
Title:
Discovery of chemical inhibitors of the selective transfer of lipids mediated by the HDL receptor SR-BI
Reference:
PNAS November 26, 2002 vol. 99 no. 24 15422-15427
Authors:
Thomas J. F. Nieland, Marsha Penman, Limor Dori, Monty Krieger, and Tomas Kirchhausen
Compounds:
BLT-1 (5234221), BLT-2 (5234225), BLT-3 (5106931), BLT-4 (5109586), BLT-5 (5117098)
INF271 (click to show)
INF271 (click to hide)
Title:
Conjugating Berberine to a Multidrug Resistance Pump Inhibitor Creates an Effective Antimicrobial
Reference:
ACS Chem Biol. 2006 Oct 24;1(9):594-600.
Authors:
Ball, Anthony R., Casadei, Gabriele, Samosorn, Siritron, Bremner, John B., Ausubel, Frederick M., Moy, Terence I. and Lewis, Kim
Compounds:
INF55 (5107950), INF271 (5109586)
INF271 (click to show)
INF271 (click to hide)
Title:
Inhibitors of bacterial multidrug efflux pumps potentiate antimicrobial photoinactivation
Reference:
Antimicrobial Agents and Chemotherapy, 2008 Sep;52(9):3202-9
Authors:
George P Tegos, Kayo Masago, Fatima Aziz, Andrew Higginbotham, Frank R Stermitz, and Michael R. Hamblin
Compounds:
INF271 (5109586)
BLT-4 (click to show)
BLT-4 (click to hide)
Title:
Host Scavenger Receptor SR-BI Plays a Dual Role in the Establishment of Malaria Parasite Liver Infection
Reference:
Cell Host & Microbe, 2008 Sep 11;4(3):271-82
Authors:
Cristina D. Rodrigues,Michael Hannus,Miguel Prudencio,Cecilie Martin,Ligia A. Goncalves,Silvia Portugal,Sabrina Epiphanio,Akin Akinc,Philipp Hadwiger,Kerstin Jahn-Hofmann,Ingo R�hl,Geert-Jan van Gemert,Jean-Francois Franetich,Adrian J.F. Luty,Robert Saue
Compounds:
BLT-1 (5234221), BLT-2 (5234225), BLT-4 (5109586), BLT-1sc (5152562)
BLT-4 (click to show)
BLT-4 (click to hide)
Title:
Cross-inhibition of SR-BI- and ABCA1-mediated cholesterol transport by the small molecules BLT-4 and glyburide
Reference:
Journal of Lipid Research 2004 Jul;45(7):1256-65. Epub 2004 Apr 21
Authors:
Thomas J. F. Nieland, Angeliki Chroni, Michael L. Fitzgerald, Zoltan Maliga, Vassilis I. Zannis, Tomas Kirchhausen, and Monty Krieger
Compounds:
BLT-4 (5109586)
BLT-4 (click to show)
BLT-4 (click to hide)
Title:
Receptor Complementation and Mutagenesis Reveal SR-BI as an Essential HCV Entry Factor and Functionally Imply Its Intra- and Extra-Cellular Domains
Reference:
PLoS Pathogens, 2009 Feb;5(2)
Authors:
Dreux, Marlene ; Dao Thi, Viet Loan ; Fresquet, Judith ; Guerin, Maryse ; Julia, Zelie ; Verney, Geraldine ; Durantel, David ; Zoulim, Fabien ; Lavillette, Dimitri ; Cosset, Francois-Loic ; Bartosch, Birke
Compounds:
BLT-4 (5109586)
BLT-4 (click to show)
BLT-4 (click to hide)
Title:
Identification of the Molecular Target of Small Molecule Inhibitors of HDL Receptor SR-BI Activity
Reference:
Biochemistry, 2008 Jan 8;47(1):460-72. Epub 2007 Dec 8.
Authors:
Thomas J. F. Nieland, Jared T. Shaw, Firoz A. Jaipuri, Jay L. Duffner, Angela N. Koehler, Sotirios Banakos, Vassilis I. Zannis, Tomas Kirchhausen, and Monty Krieger
Compounds:
Compound 1 (5136875), Compound 2 (5136871), Compound 3 (5234224), Compound 4 (5234954), Compound 5 (5554654), Compound 6 (8016115), Compound 7 (8016113), Compound 8 (5153618), Compound 9 (5136957), BLT-1 (5234221), BLT-2 (5234225), BLT-3 (5106931), BLT-4 (5109586), BLT-5 (5117098), BLT-1sc (5152562)