Bioactive Small Molecules

ethyl (2-{[(6-methyl-3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)acetyl]amino}-1,3-thiazol-4-yl)acetate

Compound 70

Compound 70 (click to show)
Compound 70 (click to hide)
Title:
Novel LRRK2 GTP-binding inhibitors reduced degeneration in Parkinson’s disease cell and mouse models
Reference:
Hum Mol Genet. 2014 Dec 1;23(23):6212-22. doi: 10.1093/hmg/ddu341. Epub 2014 Jul 3.
Authors:
Li T, Yang D, Zhong S, Thomas JM, Xue F, Liu J, Kong L, Voulalas P, Hassan HE, Park JS, MacKerell AD Jr, Smith WW
Compounds:
Compound 68 (9108605), Compound 70 (9119202)