Bioactive
Small Molecules
S30
S30 (click to show)
S30 (click to hide)
Title:
Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor.
Reference:
J Med Chem. 2014 Oct 9;57(19):8167-79. Epub 2014 Sep 29.
Authors:
Brus B, Košak U, Turk S, Pišlar A, Coquelle N, Kos J, Stojan J, Colletier JP, Gobec S.
Compounds:
S2 (
80546133
), S7 (
17036963
), S16 (
80132306
), S19 (
34521546
), S26 (
55057831
), S27 (
41107569
), S30 (
86366642
), S31 (
41107369
), S32 (
6392834
), S35 (
48315287
), S39 (
84260906
)
![1-ethyl-N-[2-(4-phenyl-1,3-thiazol-2-yl)ethyl]-3-(1-pyrrolidinylcarbonyl)-4,5,6,7-tetrahydro-1H-indazol-5-amine](/img/SC/086/86366642.jpeg "1-ethyl-N-[2-(4-phenyl-1,3-thiazol-2-yl)ethyl]-3-(1-pyrrolidinylcarbonyl)-4,5,6,7-tetrahydro-1H-indazol-5-amine")