Bioactive
Small Molecules
MCKK-4
MCKK-4 (click to show)
MCKK-4 (click to hide)
Title:
Discovery of a Novel Selective Kappa-Opioid Receptor Agonist Using Crystal Structure-Based Virtual Screening
Reference:
J Chem Inf Model. 2013 Mar 25;53(3):521-6. Epub 2013 Mar 13
Authors:
Ana Negri, Marie-Laure Rives, Michael J. Caspers, Thomas E. Prisinzano, Jonathan A. Javitch, and Marta Filizola
Compounds:
MCKK-1 (
9308518
), MCKK-4 (
84866494
), MCKK-8 (
48663789
), MCKK-15 (
15916197
), MCKK-18 (
49205801
), MCKK-21 (
14423493
), MCKK-22 (
13795991
)
![1-(1H-imidazol-4-ylmethyl)-N-[3-(1H-pyrazol-1-yl)phenyl]prolinamide](/img/SC/084/84866494.jpeg "1-(1H-imidazol-4-ylmethyl)-N-[3-(1H-pyrazol-1-yl)phenyl]prolinamide")