Bioactive Small Molecules

1'H-spiro[cyclohexane-1,4'-[1,3,5]triazino[1,2-a]benzimidazol]-2'-amine

Compound 12

Compound 12 (click to show)
Compound 12 (click to hide)
Title:
Structure-Based Discovery of Novel and Selective 5-Hydroxytryptamine 2B Receptor Antagonists for the Treatment of Irritable Bowel Syndrome.
Reference:
J Med Chem. 2016 Jan 28;59(2):707-20. Epub 2016 Jan 7.
Authors:
Zhou Y, Ma J, Lin X, Huang XP, Wu K, Huang N.
Compounds:
Compound 12 (7988754), Compound 16 (6074747)