Bioactive Small Molecules

7, Control Inhibitor, type II secretion inhibitor

Control Inhibitor (click to show)

Control Inhibitor (click to hide)

Title:

Discovery and Characterization of Inhibitors of Pseudomonas aeruginosa Type III Secretion

Reference:

Antimicrob Agents Chemother. 2010 May; 54(5): 1988-1999. Published online 2010 February 22

Authors:

Daniel Aiello, John D. Williams, Helena Majgier-Baranowska, Ishan Patel, Norton P. Peet, Jin Huang, Stephen Lory, Terry L. Bowlin, and Donald T. Moir

Compounds:

Control Inhibitor (7941790), type II secretion inhibitor (7941790), MBX 1641 (5690431), Table 3 Compound 1 (5690431), Table 3 Compound 2 (7817424), Table 3 Compound 3 (7836532), Table 3 Compound 4 {Not in our database}, Table 3 Compound 5 {Not in our database}

7 (click to show)

7 (click to hide)

Title:

Development and application of a cellular, gain-of-signal, bioluminescent reporter screen for inhibitors of type II secretion in Pseudomonas aeruginosa and Burkholderia pseudomallei

Reference:

J Biomol Screen. 2011 Aug;16(7):694-705. Epub 2011 May 20

Authors:

Moir DT, Di M, Wong E, Moore RA, Schweizer HP, Woods DE, Bowlin TL

Compounds:

1 (7790677), 2 (7801810), 3 (5339182), 4 (7935804), 5 (7936306), 6 (7939275), 7 (7941790), 8 (7939265), 9 (7917416)