Bioactive Small Molecules

2-(4-methylphenyl)-1,2-benzisothiazol-3(2H)-one

PBIT

PBIT (click to show)
PBIT (click to hide)
Title:
Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen.
Reference:
J Biol Chem. 2013 Mar 29;288(13):9408-17. doi: 10.1074/jbc.M112.419861. Epub 2013 Feb 13.
Authors:
Sayegh J, Cao J, Zou MR, Morales A, Blair LP, Norcia M, Hoyer D, Tackett AJ, Merkel JS, Yan Q.
Compounds:
PBIT (7938963)