Bioactive Small Molecules

TH-848

TH-848 (click to show)

TH-848 (click to hide)

Title:

Inhibition of microsomal prostaglandin E synthase-1 by aminothiazoles decreases prostaglandin E2 synthesis in vitro and ameliorates experimental periodontitis in vivo.

Reference:

FASEB J. 2013 Jun;27(6):2328-41. doi: 10.1096/fj.12-214445.

Authors:

Kats A, Båge T, Georgsson P, Jönsson J, Quezada HC, Gustafsson A, Jansson L, Lindberg C, Näsström K, Yucel-Lindberg T.

Compounds:

TH-848 (7882458)