Bioactive
Small Molecules
Compound 12, H2L7724589
Compound 12 (click to show)
Compound 12 (click to hide)
Title:
Structure-based drug design identifies novel LPA3 antagonists
Reference:
Bioorg Med Chem. 2009 Nov 1;17(21):7457-64. Epub 2009 Sep 18.
Authors:
James I. Fells, Ryoko Tsukahara, Jianxiong Liu, Gabor Tigyi, Abby L. Parrill
Compounds:
Compound 2 (
5105099
), Compound 4 (
5106303
), Compound 5 (
5747876
), Compound 6 (
6582859
), Compound 7 (
7886891
), Compound 8 (
5759401
), Compound 9 (
5233136
), Compound 10 (
5751335
), Compound 11 (
5770242
), Compound 12 (
7724589
), Compound 13 (
5160780
), Compound 14 (
7334533
), Compound 15 (
5750136
), Compound 16 (
7901752
), Compound 17 (
5128706
), Compound 18 (
7890363
), Compound 19 (
5233285
), Compound 20 (
5765834
)
H2L7724589 (click to show)
H2L7724589 (click to hide)
Title:
2D binary QSAR modeling of LPA3 receptor antagonism
Reference:
Journal of Molecular Graphics and Modelling, In Press, Corrected Proof, Available online 7 March 2010, ISSN 1093-3263, DOI: 10.1016/j.jmgm.2010.03.002.
Authors:
James I. Fells, Ryoko Tsukahara, Jianxiong Liu, Gabor Tigyi, Abby L. Parrill
Compounds:
H2L7724589 (
7724589
), H2L5765834 (
5765834
), Compound 8 (
6433264
), Compound 11 (
5186588
), Compound 14 (
5480696
)
![[5-(4-methylphenoxy)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]acetic acid](/img/SC/772/7724589.jpeg "[5-(4-methylphenoxy)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]acetic acid")