Bioactive
Small Molecules
E1
E1 (click to show)
E1 (click to hide)
Title:
Structural determinants of PERK inhibitor potency and selectivity
Reference:
Chem Biol Drug Des. 2010 Dec;76(6):480-95.
Authors:
Wang H, Blais J, Ron D, Cardozo T.
Compounds:
A4 (
5358394
), B2 (
5702914
), B6 (
6087220
), C1 (
6374406
), D1 (
6622172
), E1 (
7508309
), A4B2 {Author did not provide structure}, Table 2 Structure 2 (
5758028
), A4B4 {Author did not provide structure}, Table 2 Structure 4 (
5838957
)
![ethyl 2-({[(4-amino-6-oxo-1,6-dihydro-2-pyrimidinyl)thio]acetyl}amino)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate](/img/SC/750/7508309.jpeg "ethyl 2-({[(4-amino-6-oxo-1,6-dihydro-2-pyrimidinyl)thio]acetyl}amino)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate")