Bioactive Small Molecules

LF3

LF3 (click to show)

LF3 (click to hide)

Title:

A Small-Molecule Antagonist of the β-Catenin/TCF4 Interaction Blocks the Self-Renewal of Cancer Stem Cells and Suppresses Tumorigenesis

Reference:

Cancer Res. 2016 Feb 15;76(4):891-901. doi: 10.1158/0008-5472.CAN-15-1519. Epub 2015 Dec 8.

Authors:

Fang L, Zhu Q, Neuenschwander M, Specker E, Wulf-Goldenberg A, Weis WI, von Kries JP, Birchmeier W

Compounds:

LF3 (7499020)