Bioactive Small Molecules

2-methoxyethyl 4-(3-hydroxyphenyl)-7-(2-methoxyphenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydro-3-quinolinecarboxylate

HPI-1

HPI-1 (click to show)
HPI-1 (click to hide)
Title:
Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade
Reference:
Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):14132-7. Epub 2009 Aug 5.
Authors:
Hyman JM, Firestone AJ, Heine VM, Zhao Y, Ocasio CA, Han K, Sun M, Rack PG, Sinha S, Wu JJ, Solow-Cordero DE, Jiang J, Rowitch DH, Chen JK.
Compounds:
HPI-1 (7113290), HPI-2 {Not in our database}, HPI-3 {Not in our database}, HPI-4 {Not in our database}