Bioactive Small Molecules

1-(2,3-di(thiophen-2-yl) quinoxalin-6-yl)-3-(2-methoxyethyl)urea, N-(2,3-di-2-thienyl-6-quinoxalinyl)-N'-(2-methoxyethyl)urea

1-(2,3-di(thiophen-2-yl) quinoxalin-6-yl)-3-(2-methoxyethyl)urea (click to show)

1-(2,3-di(thiophen-2-yl) quinoxalin-6-yl)-3-(2-methoxyethyl)urea (click to hide)

Title:

Acetate Dependence of Tumors

Reference:

Cell. 2014 Dec 18;159(7):1591-602.

Authors:

Comerford SA, Huang Z, Du X, Wang Y, Cai L, Witkiewicz AK, Walters H, Tantawy MN, Fu A, Manning HC, Horton JD, Hammer RE, McKnight SL, Tu BP

Compounds:

N-(2,3-di-2-thienyl-6-quinoxalinyl)-N'-(2-methoxyethyl)urea (7032008), 1-(2,3-di(thiophen-2-yl) quinoxalin-6-yl)-3-(2-methoxyethyl)urea (7032008)

1-(2,3-di(thiophen-2-yl) quinoxalin-6-yl)-3-(2-methoxyethyl)urea (click to show)

1-(2,3-di(thiophen-2-yl) quinoxalin-6-yl)-3-(2-methoxyethyl)urea (click to hide)

Title:

Acetyl-CoA synthetase regulates histone acetylation and hippocampal memory

Reference:

Nature. 2017 Jun 15;546(7658):381-386. Epub 2017 May 31.

Authors:

Mews P, Donahue G, Drake AM, Luczak V, Abel T, Berger SL.

Compounds:

1-(2,3-di(thiophen-2-yl) quinoxalin-6-yl)-3-(2-methoxyethyl)urea (7032008), N-(2,3-di-2-thienyl-6-quinoxalinyl)-N'-(2-methoxyethyl)urea (7032008)