Bioactive
Small Molecules
Compound 8
Compound 8 (click to show)
Compound 8 (click to hide)
Title:
Thiobarbiturates as Sirtuin Inhibitors: Virtual Screening, Free-Energy Calculations, and Biological Testing
Reference:
ChemMedChem. 2008 Dec;3(12):1965-76.
Authors:
Urszula Uciechowska, Jorg Schemies, Robert C. Neugebauer, Elisabeth-Maria Huda
Compounds:
Compound 7 (
6958028
), Compound 8 (
6988938
), Compound 9 (
5327543
), Compound 10 (
5549466
), Compound 11 (
5240507
)
![5-[(2-hydroxy-6-methyl-3-quinolinyl)methylene]-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione](/img/SC/698/6988938.jpeg "5-[(2-hydroxy-6-methyl-3-quinolinyl)methylene]-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione")