Bioactive Small Molecules

6973856, Analog 74, Compound 44

Analog 74 (click to show)

Analog 74 (click to hide)

Title:

6-Oxo and 6-Thio Purine Analogs as Antimycobacterial Agents

Reference:

Bioorg Med Chem. 2013 Apr 1;21(7):1685-95.

Authors:

Ashish K. Pathak, Vibha Pathak, Lainne E. Seitz, William J. Suling, Robert C. Reynolds

Compounds:

Analog 74 (6973856)

6973856 (click to show)

6973856 (click to hide)

Title:

Current Status and Research Strategies in Tuberculosis Drug Development

Reference:

J Med Chem. 2011 Sep 22;54(18):6157-65. doi: 10.1021/jm200305q. Epub 2011 Aug 16.

Authors:

Lynn G. Dover and Geoffrey D. Coxon

Compounds:

7169188 (7169188), 6958998 (6958998), 6973856 (6973856), 7128202 (7128202), 6658399 (6658399)

Compound 44 (click to show)

Compound 44 (click to hide)

Title:

High-throughput screening for inhibitors of Mycobacterium tuberculosis H37Rv

Reference:

Tuberculosis, Volume 89, Issue 5, Theme: New Drug Development; Chemical Genomic Tools and Drug Leads from High-throughput Screening against Mycobacterium tuberculosis, September 2009, Pages 334-353, ISSN 1472-9792, DOI: 10.1016/j.tube.2009.05.008.

Authors:

Subramaniam Ananthan, Ellen R. Faaleolea, Robert C. Goldman, Judith V. Hobrath, Cecil D. Kwong, Barbara E. Laughon, Joseph A. Maddry, Alka Mehta, Lynn Rasmussen, Robert C. Reynolds, John A. Secrist III, Nice Shindo, Dustin N. Showe, Melinda I. Sosa, Willia

Compounds:

Compound 44 (6973856)