Bioactive Small Molecules

methyl 5-(cyclooctylamino)-1-(2-methoxyethyl)-3-[(phenylacetyl)amino]-1H-pyrrolo[2,3-b]pyridine-2-carboxylate

IND3

IND3 (click to show)
IND3 (click to hide)
Title:
Differences in conformational dynamics between Plasmodium falciparum and human Hsp90 orthologues enable the structure-based discovery of pathogen-selective inhibitors.
Reference:
J Med Chem. 2014 Mar 27;57(6):2524-35. Epub 2014 Mar 3.
Authors:
Wang T, Bisson WH, Mäser P, Scapozza L, Picard D.
Compounds:
IND3 (68644494), IND31119 (43190295), IND311 (27375659), IND31120 (47572559), IND3111910 (34185989)