Bioactive Small Molecules

N-(4-{[(3-methoxy-2-pyrazinyl)amino]sulfonyl}phenyl)-3-(5-nitro-2-thienyl)acrylamide

Necrosulphonamide

Necrosulphonamide (click to show)
Necrosulphonamide (click to hide)
Title:
Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis.
Reference:
Nat Cell Biol. 2014 Jan;16(1):55-65. doi: 10.1038/ncb2883. Epub 2013 Dec 8.
Authors:
Cai Z, Jitkaew S, Zhao J, Chiang HC, Choksi S, Liu J, Ward Y, Wu LG, Liu ZG.
Compounds:
Necrosulphonamide (6838475)