Bioactive Small Molecules

2-bromo-N-(3-methylphenyl)-5-(1-piperidinylsulfonyl)benzamide

6670011

6670011 (click to show)
6670011 (click to hide)
Title:
A Brain-Permeable Small Molecule Reduces Neuronal Cholesterol by Inhibiting Activity of Sirtuin 2 Deacetylase
Reference:
ACS Chem Biol. 2011 Jun 17;6(6):540-6. doi: 10.1021/cb100376q. Epub 2011 Mar 9.
Authors:
David M. Taylor, Uma Balabadra, Zhongmin Xiang, Ben Woodman, Sarah Meade, Allison Amore, Michele M. Maxwell, Steven Reeves, Gillian P. Bates, Ruth Luthi-Carter, Philip A. S. Lowden, and Aleksey G. Kazantsev
Compounds:
6648610 (6648610), 6666243 (6666243), 6680310 (6680310), 6670011 (6670011), AK-7 (6672313), AK-1 (6642056), 5210809 (5210809)
6670011 (click to show)
6670011 (click to hide)
Title:
A Forward Chemical Screen Identifies Antibiotic Adjuvants in Escherichia coli
Reference:
ACS Chem Biol. 2012 Sep 21;7(9):1547-55. Epub 2012 Jun 22.
Authors:
Patricia L. Taylor, Laura Rossi, Gianfranco De Pascale, and Gerard D. Wright
Compounds:
C2-10-1 (5346237), C2-10-2 (5921967), 6680310 (6671446), 6670011 (6670011), AK-7 (6672313), AK-1 (6642056), 5210809 (5914543)