Bioactive Small Molecules

15, LOXBlock-2

LOXBlock-2 (click to show)

LOXBlock-2 (click to hide)

Title:

Novel Lipoxygenase Inhibitors as Neuroprotective Reagents

Reference:

Journal of Neuroscienc Research, 2008 Mar;86(4):904-9

Authors:

Klaus van Leyen, Ken Arai, Guang Jin, Victor Kenyon, Bettina Gerstner, Paul A. Rosenberg, Theodore R. Holman, and Eng H. Lo

Compounds:

LOXBlock-1 (5680672), LOXBlock-2 (6635967), LOXBlock-3 (6640337)

15 (click to show)

15 (click to hide)

Title:

Novel Human Lipoxygenase Inhibitors Discovered Using Virtual Screening with Homology Models

Reference:

J. Med. Chem., 2006 Feb 23;49(4):1356-63

Authors:

Victor Kenyon, Ilya Chorny, Wendy J. Carvajal, Theodore R. Holman, and Matthew P. Jacobson

Compounds:

15 (6635967), 12 (5680672), 9 (6640337)