Bioactive Small Molecules

7-{(2,3-dichlorophenyl)[(4-methyl-2-pyridinyl)amino]methyl}-8-quinolinol

MMRi64

MMRi64 (click to show)
MMRi64 (click to hide)
Title:
Targeting RING domains of Mdm2-MdmX E3 complex activates apoptotic arm of the p53 pathway in leukemia/lymphoma cells
Reference:
Cell Death Dis. 2015 Dec 31;6:e2035.
Authors:
Wu W, Xu C, Ling X, Fan C, Buckley BP, Chernov MV, Ellis L, Li F, Munoz IG, Wang X.
Compounds:
MMRi6 (7887535), MMRi64 (6635933)