Bioactive Small Molecules

NPF-1

NPF-1 (click to show)

NPF-1 (click to hide)

Title:

Changes in PSAC Reduce Leupeptin Uptake and Can Confer Drug Resistance in P. falciparum-Infected Erythrocytes

Reference:

Antimicrob Agents Chemother. 2008 Jul;52(7):2346-54. Epub 2008 Apr 28.

Authors:

Godfrey Lisk, Margaret Pain, Ilya Y. Gluzman, Shivkumar Kambhampati, Tetsuya Furuya, Xin-zhuan Su, Michael P. Fay, Daniel E. Goldberg, and Sanjay A. Desai

Compounds:

NPF-1 (6574929)

NPF-1 (click to show)

NPF-1 (click to hide)

Title:

Malaria Parasites Are Rapidly Killed by Dantrolene Derivatives Specific for the Plasmodial Surface Anion Channel

Reference:

Mol Pharmacol 2005 Jul;68(1):34-40

Authors:

Myungsa Kang, Godfrey Lisk, Stephen Hollingworth, Stephen M. Baylor, and Sanjay A. Desai

Compounds:

NPF-1 (6574929), NPF-2 (6435597)