Bioactive
Small Molecules
Compound 1, MLS000062185
Compound 1 (click to show)
Compound 1 (click to hide)
Title:
Ranking the selectivity of PubChem screening hits by activity-based protein profiling: MMP13 as a case study
Reference:
Bioorg Med Chem. 2009 Feb 1;17(3):1101-8. Epub 2008 Mar 8.
Authors:
Ryuichiro Nakai, Cleo M. Salisbury, Hugh Rosen, Benjamin F. Cravatt
Compounds:
Compound 1 (
6512965
), Compound 2 (
5942399
)
MLS000062185 (click to show)
MLS000062185 (click to hide)
Title:
High throughput screening of potentially selective MMP-13 exosite inhibitors utilizing a triple-helical FRET substrate
Reference:
Bioorg Med Chem. 2009 Feb 1;17(3):990-1005.
Authors:
Lauer-Fields JL, Minond D, Chase PS, Baillargeon PE, Saldanha SA, Stawikowska R, Hodder P, Fields GB.
Compounds:
MLS000051260 (
7925560
), MLS000111675 (
6370266
), MLS000105542 (
5161874
), MLS000108799 (
5927508
), MLS000049833 (
7894782
), MLS000096979 (
7685300
), MLS000062315 (
6624994
), MLS000062185 (
6512965
), MLS000104229 (
5215570
), MLS000043319 (
7461374
), MSL000106248 (
5344221
)
![2-[(4-chlorobenzyl)thio]-3,5,6,7-tetrahydro-4H-cyclopenta[d]pyrimidin-4-one](/img/SC/651/6512965.jpeg "2-[(4-chlorobenzyl)thio]-3,5,6,7-tetrahydro-4H-cyclopenta[d]pyrimidin-4-one")