Bioactive Small Molecules

Tenovin-1

Tenovin-1 (click to show)

Tenovin-1 (click to hide)

Title:

Discovery, In Vivo Activity, and Mechanism of Action of a Small-Molecule p53 Activator

Reference:

Cancer Cell, 2008 May;13(5):454-63

Authors:

Sonia Lain,Jonathan J. Hollick,Johanna Campbell,Oliver D. Staples,Maureen Higgins,Mustapha Aoubala,Anna McCarthy,Virginia Appleyard,Karen E. Murray,Lee Baker,Alastair Thompson,Joanne Mathers,Stephen J. Holland,Michael J.R. Stark,Georgia Pass,Julie Woods,Da

Compounds:

Tenovin-1 (6504104)

Tenovin-1 (click to show)

Tenovin-1 (click to hide)

Title:

The discovery of nongenotoxic activators of p53: Building on a cell-based high-throughput screen

Reference:

Seminars in Cancer Biology, 2010 Feb;20(1):40-5. Epub 2010 Mar 4.

Authors:

Anna R. McCarthy, Jonathan J. Hollick, Nicholas J. Westwood

Compounds:

Tenovin-1 (6504104), Prima-1 {Not in our database}, 9AA {Not in our database}, KCG165 {Not in our database}