Bioactive Small Molecules

Compound 16

Compound 16 (click to show)

Compound 16 (click to hide)

Title:

Ebselen inhibits hepatitis C virus NS3 helicase binding to nucleic acid and prevents viral replication.

Reference:

ACS Chem Biol. 2014 Oct 17;9(10):2393-403. Epub 2014 Aug 15.

Authors:

Mukherjee S, Weiner WS, Schroeder CE, Simpson DS, Hanson AM, Sweeney NL, Marvin RK, Ndjomou J, Kolli R, Isailovic D, Schoenen FJ, Frick DN.

Compounds:

Compound 18 (6238046), Compound 16 (6239307), Compound 17 (5133201)