Bioactive Small Molecules

1-(2-bromo-4-methylphenyl)-1H-pyrrole-2,5-dione

Compound 18

Compound 18 (click to show)
Compound 18 (click to hide)
Title:
Ebselen inhibits hepatitis C virus NS3 helicase binding to nucleic acid and prevents viral replication.
Reference:
ACS Chem Biol. 2014 Oct 17;9(10):2393-403. Epub 2014 Aug 15.
Authors:
Mukherjee S, Weiner WS, Schroeder CE, Simpson DS, Hanson AM, Sweeney NL, Marvin RK, Ndjomou J, Kolli R, Isailovic D, Schoenen FJ, Frick DN.
Compounds:
Compound 18 (6238046), Compound 16 (6239307), Compound 17 (5133201)