Bioactive Small Molecules

6094911, Fasentin

6094911 (click to show)

6094911 (click to hide)

Title:

Identification of Small Molecules that Sensitize Resistant Tumor Cells to Tumor Necrosis Factor-Family Death Receptors

Reference:

Cancer Res 2006; 66(4): 2367-75

Authors:

Aaron D. Schimmer, Michael P. Thomas, Rose Hurren, Marcela Gronda, Maurizio Pellecchia, Gregory R. Pond, Marina Konopleva, Debbie Gurfinkel, Imtiaz A. Mawji, Ewan Brown, and John C. Reed

Compounds:

6094911 (6094911), 5809354 (5809354), 5703229 (5703229), 5541203 (5541203), 5687158 (5687158), 5557608 (5557608), 5647994 (5647994), 5362611 (5362611), 5569100 (5569100)

Fasentin (click to show)

Fasentin (click to hide)

Title:

A novel inhibitor of glucose uptake sensitizes cells to FAS-induced cell death

Reference:

Mol Cancer Ther 2008 Nov;7(11):3546-55

Authors:

Tabitha E. Wood, Shadi Dalili, Craig D. Simpson, Rose Hurren, Xinliang Mao, Fernando Suarez Saiz, Marcela Gronda, Yanina Eberhard, Mark D. Minden, Philip J. Bilan, Amira Klip, Robert A. Batey and Aaron D. Schimmer

Compounds:

Fasentin (6094911)