Bioactive Small Molecules

2-thioxo-5-[(1,2,5-trimethyl-1H-pyrrol-3-yl)methylene]dihydro-4,6(1H,5H)-pyrimidinedione

Compound 4

Compound 4 (click to show)
Compound 4 (click to hide)
Title:
Differential response of orthologous L,L-diaminopimelate aminotransferases (DapL) to enzyme inhibitory antibiotic lead compounds
Reference:
Bioorg Med Chem. 2014 Jan 1;22(1):523-30. doi: 10.1016/j.bmc.2013.10.055. Epub 2013 Nov 9.
Authors:
McKinnie SM, Rodriguez-Lopez EM, Vederas JC, Crowther JM, Suzuki H, Dobson RC, Leustek T, Triassi AJ, Wheatley MS, Hudson AO
Compounds:
Compound 1 (5925714), Compound 2 (6523070), Compound 3 (6072466), Compound 4 (6088649)