Bioactive
Small Molecules
Compound 1
Compound 1 (click to show)
Compound 1 (click to hide)
Title:
Small Molecule Inhibitors of the MDM2-p53 Interaction Discovered by Ensemble-Based Receptor Models
Reference:
J. Am. Chem. Soc., 2007 Oct 24;129(42):12809-14. Epub 2007 Sep 29.
Authors:
Anna L. Bowman, Zaneta Nikolovska-Coleska, Haizhen Zhong, Shaomeng Wang, and Heather A. Carlson
Compounds:
Compound 1 (
6035242
), Compound 2 (
5478812
), Compound 3 (
5359503
), Compound 4 (
5918640
)
![2-amino-6-{[2-(3,4-dihydroxyphenyl)-2-oxoethyl]thio}-4-(4-hydroxyphenyl)-3,5-pyridinedicarbonitrile](/img/SC/603/6035242.jpeg "2-amino-6-{[2-(3,4-dihydroxyphenyl)-2-oxoethyl]thio}-4-(4-hydroxyphenyl)-3,5-pyridinedicarbonitrile")