Bioactive Small Molecules

ITX3

ITX3 (click to show)

ITX3 (click to hide)

Title:

A Cell Active Chemical GEF Inhibitor Selectively Targets the Trio/RhoG/Rac1 Signaling Pathway

Reference:

Chemistry & Biology, 2009 Jun 26;16(6):657-66.

Authors:

Nathalie Bouquier, Emmanuel Vignal, Sophie Charrasse, Mylene Weill, Susanne Schmidt, Jean-Paul Leonetti, Anne Blangy, Philippe Fort

Compounds:

ITX1 (6170085), NPPD (5133201), ITX3 (6007262)

ITX3 (click to show)

ITX3 (click to hide)

Title:

Neuronal growth cone retraction relies on proneurotrophin receptor signaling through Rac

Reference:

Sci Signal. 2011 Dec 6;4(202):ra82. doi: 10.1126/scisignal.2002060.

Authors:

Deinhardt K, Kim T, Spellman DS, Mains RE, Eipper BA, Neubert TA, Chao MV, Hempstead BL.

Compounds:

ITX3 (6007262)