Bioactive Small Molecules

1-(3-bromophenyl)-5-(2-furylmethylene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione

SMIFH2

SMIFH2 (click to show)
SMIFH2 (click to hide)
Title:
Identification and Characterization of a Small Molecule Inhibitor of Formin-Mediated Actin Assembly
Reference:
Chemistry and Biology, Volume 16, Issue 11, 25 November 2009, Pages 1158-1168
Authors:
Syed A. Rizvi, Erin M. Neidt, Jiayue Cui, Zach Feiger, Colleen T. Skau, Margaret L. Gardel, Sergey A. Kozmin and David R. Kovar
Compounds:
SMIFH2 (5992446), Analog 2 (6062767), Analog 7 (6062214)