Bioactive Small Molecules

Compound 1, Compound C-1

Compound C-1 (click to show)

Compound C-1 (click to hide)

Title:

Exploration of inhibitors for diaminopimelate aminotransferase

Reference:

Bioorganic & Medicinal Chemistry, 2010 Mar 15;18(6):2141-51. doi: 10.1016/j.bmc.2010.02.001. Epub 2010 Feb 6.

Authors:

Chenguang Fan, Matthew D. Clay, Michael K. Deyholos, John C. Vederas

Compounds:

Compound C-1 (5925714)

Compound 1 (click to show)

Compound 1 (click to hide)

Title:

Differential response of orthologous L,L-diaminopimelate aminotransferases (DapL) to enzyme inhibitory antibiotic lead compounds

Reference:

Bioorg Med Chem. 2014 Jan 1;22(1):523-30. doi: 10.1016/j.bmc.2013.10.055. Epub 2013 Nov 9.

Authors:

McKinnie SM, Rodriguez-Lopez EM, Vederas JC, Crowther JM, Suzuki H, Dobson RC, Leustek T, Triassi AJ, Wheatley MS, Hudson AO

Compounds:

Compound 1 (5925714), Compound 2 (6523070), Compound 3 (6072466), Compound 4 (6088649)