Bioactive Small Molecules

2-benzyl-1-[(4-hydroxyphenyl)amino]-3-methylpyrido[1,2-a]benzimidazole-4-carbonitrile

SE486-11

SE486-11 (click to show)
SE486-11 (click to hide)
Title:
A novel combination therapy targeting ubiquitin-specific protease 5 in MYCN-driven neuroblastoma
Reference:
Oncogene . 2021 Mar 3. doi: 10.1038/s41388-021-01712-w. Online ahead of print.
Authors:
Belamy B Cheung, Ane Kleynhans, Rituparna Mittra, Patrick Y Kim, Jessica K Holien, Zsuzsanna Nagy, Olivia C Ciampa, Janith A Seneviratne, Chelsea Mayoh, Mukesh Raipuria, Satyanarayana Gadde, Hassina Massudi, Iris Poh Ling Wong, Owen Tan, Andrew Gong, Aldwin Suryano, Sonya M Diakiw, Bing Liu, Greg M Arndt, Tao Liu, Naresh Kumar, Olle Sangfelt, Shizhen Zhu, Murray D Norris, Michelle Haber, Daniel R Carter, Michael W Parker, Glenn M Marshall
Compounds:
SE486-11 (5870103)