Bioactive Small Molecules

AGK2

AGK2 (click to show)

AGK2 (click to hide)

Title:

Linking SIRT2 to Parkinsons Disease

Reference:

ACS Chemical Biology, 2007 Aug 17;2(8):529-32.

Authors:

Adam L. Garske, Brian C. Smith, and John M. Denu

Compounds:

B2 (6133799), AGK2 (5857140), AK-1 (6642056)

AGK2 (click to show)

AGK2 (click to hide)

Title:

Sirtuin 2 Inhibitors Rescue a-Synuclein-Mediated Toxicity in Models of Parkinson's Disease

Reference:

Science 2007 Jul 27;317(5837):516-9

Authors:

Tiago Fleming Outeiro, Eirene Kontopoulos, Stephen M. Altmann, Irina Kufareva, Katherine E. Strathearn, Allison M. Amore, Catherine B. Volk, Michele M. Maxwell, Jean-Christophe Rochet, Pamela J. McLean, Anne B. Young, Ruben Abagyan, Mel B. Feany, Bradley

Compounds:

AGK2 (5857140), AK-1 (6642056)