Bioactive Small Molecules

NBD-556

NBD-556 (click to show)

NBD-556 (click to hide)

Title:

Novel Antiviral Agents Targeting HIV Entry and Transmission

Reference:

VIROLOGICA SINICA, December 2007, 22 (6):451-461

Authors:

Qinxue Hu and Robin Shattock

Compounds:

NBD-556 (5849968), NBD-557 (5857355)

NBD-556 (click to show)

NBD-556 (click to hide)

Title:

Thermodynamics of Binding of a Low-Molecular-Weight CD4 Mimetic to HIV-1 gp120

Reference:

Biochemistry, 2006 Sep 12;45(36):10973-80

Authors:

Arne Schoen, Navid Madani, Jeffrey C. Klein, Amy Hubicki, Danny Ng, Xinzhen Yang, Amos B. Smith, III, Joseph Sodroski, and Ernesto Freire

Compounds:

NBD-556 (5849968), NBD-557 (5857355)

NBD-556 (click to show)

NBD-556 (click to hide)

Title:

Identification of N-phenyl-N?-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamides as a new class of HIV-1 entry inhibitors that prevent gp120 binding to CD4

Reference:

Virology, 2005 Sep 1;339(2):213-25.

Authors:

Qian Zhaoa, Liying Maa, Shibo Jiangb, Hong Lub, Shuwen Liub, Yuxian Heb, Nathan Strickc, Nouri Neamatid and Asim Kumar Debnatha

Compounds:

NBD-556 (5849968), NBD-557 (5857355)