Bioactive
Small Molecules
Lipofermata, SIT-4
Lipofermata (click to show)
Lipofermata (click to hide)
Title:
Chemical inhibition of fatty acid absorption and cellular uptake limits lipotoxic cell death
Reference:
Biochem Pharmacol. 2015 Nov 1;98(1):167-81. doi: 10.1016/j.bcp.2015.09.004. Epub 2015 Sep 21.
Authors:
Ahowesso C, Black PN, Saini N, Montefusco D, Chekal J, Malosh C, Lindsley CW, Stauffer SR, DiRusso CC
Compounds:
Lipofermata (
5830995
)
SIT-4 (click to show)
SIT-4 (click to hide)
Title:
Zinc Chelation by a Small-Molecule Adjuvant Potentiates Meropenem Activity in Vivo against NDM-1-Producing Klebsiella pneumoniae
Reference:
ACS Infect. Dis., 2015, 1 (11), pp 533–543. Epub 8 May 2015.
Authors:
Falconer SB, Reid-Yu SA, King AM, Gehrke SS, Wang W, Britten JF, Coombes BK, Wright GD, and Brown ED.
Compounds:
SIT-1 (
5677976
), SIT-2 (
5668345
), SIT-3 (
5675594
), SIT-4 (
5830995
), SIT-Z5 (
5833514
), SIT-Z1 (
5681294
), SIT-Z2 {Not in our database}, SIT-Z3 {Not in our database}, SIT-Z4 {Not in our database}, SIT-Z5 (
5833514
), SIT-Z6 {Not in our database}, SIT-5 (
5674906
)
![5-bromo-5'-phenyl-3'H-spiro[indole-3,2'-[1,3,4]thiadiazol]-2(1H)-one](/img/SC/583/5830995.jpeg "5-bromo-5'-phenyl-3'H-spiro[indole-3,2'-[1,3,4]thiadiazol]-2(1H)-one")