Bioactive Small Molecules

4-(4-chloro-2-methylphenoxy)-N-hydroxybutanamide

5809354

5809354 (click to show)
5809354 (click to hide)
Title:
Identification of Small Molecules that Sensitize Resistant Tumor Cells to Tumor Necrosis Factor-Family Death Receptors
Reference:
Cancer Res 2006; 66(4): 2367-75
Authors:
Aaron D. Schimmer, Michael P. Thomas, Rose Hurren, Marcela Gronda, Maurizio Pellecchia, Gregory R. Pond, Marina Konopleva, Debbie Gurfinkel, Imtiaz A. Mawji, Ewan Brown, and John C. Reed
Compounds:
6094911 (6094911), 5809354 (5809354), 5703229 (5703229), 5541203 (5541203), 5687158 (5687158), 5557608 (5557608), 5647994 (5647994), 5362611 (5362611), 5569100 (5569100)
5809354 (click to show)
5809354 (click to hide)
Title:
Discovery of inhibitors of Schistosoma mansoni HDAC8 by combining homology modeling, virtual screening, and in vitro validation.
Reference:
J Chem Inf Model. 2014 Oct 27;54(10):3005-19. Epub 2014 Oct 2.
Authors:
Kannan S, Melesina J, Hauser AT, Chakrabarti A, Heimburg T, Schmidtkunz K, Walter A, Marek M, Pierce RJ, Romier C, Jung M, Sippl W.
Compounds:
5144030 (5144030), 5158497 (5158497), 5234974 (5234974), 5808200 (5808200), 5809354 (5809354), 6022898 (6022898), 7778127 (7778127), 8879700 (8879700)