Bioactive Small Molecules

Cmpd I, SKI I

Cmpd I (click to show)

Cmpd I (click to hide)

Title:

Discovery and Evaluation of Inhibitors of Human Sphingosine Kinase

Reference:

CANCER RESEARCH 2003 Sep 15;63(18):5962-9

Authors:

Kevin J. French, Randy S. Schrecengost, Brian D. Lee, Yan Zhuang, Staci N. Smith, Justin L. Eberly, Jong K. Yun, and Charles D. Smith

Compounds:

Cmpd I (5784220), Cmpd II (5663543), Cmpd III (5679119), Cmpd IV (5318164)

SKI I (click to show)

SKI I (click to hide)

Title:

Antitumor Activity of Sphingosine Kinase Inhibitors

Reference:

J Pharmacol Exp Ther. 2006 Aug;318(2):596-603

Authors:

Kevin J. French, John J. Upson, Staci N. Keller, Yan Zhuang, Jong K. Yun, and Charles D. Smith

Compounds:

SKI I (5784220), SKI II (5663543)