Bioactive Small Molecules

5767664, Pthaladyn-1

5767664 (click to show)

5767664 (click to hide)

Title:

Target-Specific Support Vector Machine Scoring in Structure-Based Virtual Screening: Computational Validation, In Vitro Testing in Kinases, and Effects on Lung Cancer Cell Proliferation

Reference:

J Chem Inf Model. 2011 Apr 25;51(4):755-9. Epub 2011 Mar 25.

Authors:

Liwei Li, May Khanna, Inha Jo, Fang Wang, Nicole M. Ashpole, Andy Hudmon, and Samy O. Meroueh

Compounds:

6547174 (6547174), 5767664 (5767664), 8882059 (8882059),

Pthaladyn-1 (click to show)

Pthaladyn-1 (click to hide)

Title:

The Pthaladyns: GTP Competitive Inhibitors of Dynamin I and II GTPase Derived from Virtual Screening

Reference:

Journal of Medicinal Chemistry 2010 53 (14), 5267-5280

Authors:

Luke R. Odell, Dian Howan, Christopher P. Gordon, Mark J. Robertson, Ngoc Chau, Anna Mariana, Ainslie E. Whiting, Ruben Abagyan, James A. Daniel, Nick N. Gorgani, Phillip J. Robinson, Adam McCluskey

Compounds:

Pthaladyn-1 (5767664), Pthaladyn-23 {Not in our database}, Pthaladyn-29 {Not in our database}