Bioactive Small Molecules

2-phenylethyl 2-methyl-4-(2-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydro-3-quinolinecarboxylate

MP576

MP576 (click to show)
MP576 (click to hide)
Title:
Identification of Novel Small-Molecule Inhibitors of Severe Acute Respiratory Syndrome-Associated Coronavirus by Chemical Genetics
Reference:
Chemistry & Biology, Vol. 11, 1293-1299, September, 2004,
Authors:
Richard Y. Kao, Wayne H.W. Tsui, Terri S.W. Lee, Julian A. Tanner, Rory M. Watt, Jian-Dong Huang, Lihong Hu, Guanhua Chen, Zhiwei Chen, Linqi Zhang, Tian He, Kwok-Hung Chan, Herman Tse, Amanda P.C. To, Louisa W.Y. Ng, Bonnie C.W. Wong, Hoi-Wah Tsoi, Dan Ya
Compounds:
MP576 (5763678), HE602 (6026920), VE607 (6075949)
MP576 (click to show)
MP576 (click to hide)
Title:
Characterization of SARS-CoV main protease and identification of biologically active small molecule inhibitors using a continuous fluorescence-based assay
Reference:
FEBS Letters 2004 Oct 22;576(3):325-30.
Authors:
Kao, R.Y.;To, A.P.C.;Ng, L.W.Y.;Tsui, W.H.W.;Lee, T.S.W.;Tsoi, H.-W.;Yuen, K.-Y.;
Compounds:
MP521 (5215394), CB5751 (5751077), CB5173 (5173015), MP576 (5763678)