Bioactive Small Molecules

4B

4B (click to show)

4B (click to hide)

Title:

Phenotype-based Discovery of 2-[(E)-2-(Quinolin-2-yl)vinyl]phenol as a Novel Regulator of Ocular Angiogenesis

Reference:

J Biol Chem. 2016 Feb 4. pii: jbc.M115.710665. [Epub ahead of print]

Authors:

Reynolds AL, Alvarez Y, Sasore T, Waghorne N, Butler C, Kilty C, Smith AJ, McVicar C, Wong VH, Galvin O, Merrigan S, Osman J, Grebnev G, Sjölander A, Stitt AW, Kennedy BN

Compounds:

2-[(E)-2-(quinolin-2-yl)vinyl]phenol (5719593), quininib (5719593), 3B (5761460), 11F (5684285), 4B (5761893)