Bioactive
Small Molecules
3B
3B (click to show)
3B (click to hide)
Title:
Phenotype-based Discovery of 2-[(E)-2-(Quinolin-2-yl)vinyl]phenol as a Novel Regulator of Ocular Angiogenesis
Reference:
J Biol Chem. 2016 Feb 4. pii: jbc.M115.710665. [Epub ahead of print]
Authors:
Reynolds AL, Alvarez Y, Sasore T, Waghorne N, Butler C, Kilty C, Smith AJ, McVicar C, Wong VH, Galvin O, Merrigan S, Osman J, Grebnev G, Sjölander A, Stitt AW, Kennedy BN
Compounds:
2-[(E)-2-(quinolin-2-yl)vinyl]phenol (
5719593
), quininib (
5719593
), 3B (
5761460
), 11F (
5684285
), 4B (
5761893
)
![methyl 4-{2,5-dioxo-3-[4-(2-pyrimidinyl)-1-piperazinyl]-1-pyrrolidinyl}benzoate](/img/SC/576/5761460.jpeg "methyl 4-{2,5-dioxo-3-[4-(2-pyrimidinyl)-1-piperazinyl]-1-pyrrolidinyl}benzoate")