Bioactive Small Molecules

2-{[3-cyano-6-cyclopropyl-4-(4-methoxyphenyl)-2-pyridinyl]thio}acetamide

SANT-3

SANT-3 (click to show)
SANT-3 (click to hide)
Title:
Small molecule modulation of HH-GLI signaling: Current leads, trials and tribulations
Reference:
Biochem Pharmacol. 2010 Sep 1;80(5):712-23. Epub 2010 Apr 20.
Authors:
Mas C, Altaba AR.
Compounds:
SANT-1 (5786262), SANT-2 (5800831), SANT-3 (5725940), SANT-4 (5568598), TC-132 {Not in our database}
SANT-3 (click to show)
SANT-3 (click to hide)
Title:
Small molecule modulation of Smoothened activity
Reference:
PNAS October 29, 2002 vol. 99 no. 22 14071-14076
Authors:
James K. Chen, Jussi Taipale, Keith E. Young, Tapan Maiti, and Philip A. Beachy
Compounds:
SANT-1 (5786262), SANT-2 (5800831), SANT-3 (5725940), SANT-4 (5568598)
SANT-3 (click to show)
SANT-3 (click to hide)
Title:
Small molecule modulation of Smoothened activity
Reference:
PNAS 2002 Oct 29;99(22):14071-6.
Authors:
Chen JK, Taipale J, Young KE, Maiti T, Beachy PA.
Compounds:
SANT-1 (5786262), SANT-2 (5800831), SANT-3 (5725940), SANT-4 (5568598)