Bioactive Small Molecules

341001-38-5, Compound 1, Compound FA-4, Nucleozin

nucleozin (click to show)

nucleozin (click to hide)

Title:

Development of an Anti-Influenza Drug Screening Assay Targeting Nucleoproteins with Tryptophan Fluorescence Quenching

Reference:

Anal Chem. 2012 Aug 7;84(15):6391-9. doi: 10.1021/ac2022426. Epub 2012 Jul 10.

Authors:

Hui-Chen Hung, Chia-Lin Liu, John T.-A. Hsu, Jim-Tong Horng, Ming-Yu Fang, Su-Ying Wu, Shau-Hua Ueng, Min-Ying Wang, Cheng-Wen Yaw, and Ming-Hon Hou

Compounds:

nucleozin (5713492), CSV0C001018 (5554427)

341001-38-5 (click to show)

341001-38-5 (click to hide)

Title:

Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers

Reference:

Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15366-71. Epub 2011 Sep 6.

Authors:

Gerritz SW, Cianci C, Kim S, Pearce BC, Deminie C, Discotto L, McAuliffe B, Minassian BF, Shi S, Zhu S, Zhai W, Pendri A, Li G, Poss MA, Edavettal S, McDonnell PA, Lewis HA, Maskos K, Mörtl M, Kiefersauer R, Steinbacher S, Baldwin ET, Metzler W, Bryson J,

Compounds:

Compound 1 (5713492), 341001-38-5 (5713492), Compound 2 {}, 312537-30-7 {}

Compound FA-4 (click to show)

Compound FA-4 (click to hide)

Title:

Identification of influenza A nucleoprotein as an antiviral target

Reference:

Nat Biotechnol. 2010 Jun;28(6):600-5. Epub 2010 May 30

Authors:

Kao RY, Yang D, Lau LS, Tsui WH, Hu L, Dai J, Chan MP, Chan CM, Wang P, Zheng BJ, Sun J, Huang JD, Madar J, Chen G, Chen H, Guan Y, Yuen KY.

Compounds:

Nucleozin (5713492), Compound FA-4 (5713492)