Bioactive Small Molecules

methyl 2-[(pentafluorobenzoyl)amino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate

TP2

TP2 (click to show)
TP2 (click to hide)
Title:
Antituberculosis thiophenes define a requirement for Pks13 in mycolic acid biosynthesis
Reference:
Nat Chem Biol. 2013 Aug;9(8):499-506. doi: 10.1038/nchembio.1277. Epub 2013 Jun 16.
Authors:
Wilson R, Kumar P, Parashar V, Vilchèze C, Veyron-Churlet R, Freundlich JS, Barnes SW, Walker JR, Szymonifka MJ, Marchiano E, Shenai S, Colangeli R, Jacobs WR Jr, Neiditch MB, Kremer L, Alland D.
Compounds:
TP2 (5696114), TP4 (7242087)