Bioactive Small Molecules

5673765, Compound 4

5673765 (click to show)

5673765 (click to hide)

Title:

Inhibition of Hematopoietic Protein Tyrosine Phosphatase Augments and Prolongs ERK1/2 and p38 Activation

Reference:

ACS Chem Biol. 2012 Feb 17;7(2):367-77. doi: 10.1021/cb2004274. Epub 2011 Nov 17.

Authors:

Eduard Sergienko, Jian Xu, Wallace H. Liu, Russell Dahl, David A. Critton, Ying Su, Brock T. Brown, Xochella Chan, Li Yang, Ekaterina V. Bobkova, Stefan Vasile, Hongbin Yuan, Justin Rascon, Sharon Colayco, Shyama Sidique, Nicholas D. P. Cosford, Thomas D.

Compounds:

5682472 (5682472), 5673765 (5673765), 5673461 (5673461), 7037688 (7037688), 5679657 (5679657), 5671090 (5671090), 6722914 (6722914), 7796860 (7796860), 5684068 (5684068)

Compound 4 (click to show)

Compound 4 (click to hide)

Title:

Parallel Multiplicative Target Screening against Divergent Bacterial Replicases: Identification of Specific Inhibitors with Broad Spectrum Potential

Reference:

Biochemistry 2010 Mar 23;49(11):2551-62

Authors:

H. Garry Dallmann, Oliver J. Fackelmayer, Guy Tomer, Joe Chen, Anna Wiktor-Becker, Tracey Ferrara, Casey Pope, Marcos T. Oliveira, Peter M. J. Burgers, Laurie S. Kaguni, Charles S. McHenry

Compounds:

Compound 4 (5673765), Compound 345 (5424294), Compound 309 (5175324), Compound 285 (5996663), Compound 153 (5652994), Compound 161 {Not in our database}, Compound 72 {Not in our database}