Bioactive Small Molecules

5-ethyl-5'-phenyl-3'H-spiro[indole-3,2'-[1,3,4]thiadiazol]-2(1H)-one

SIT-2

SIT-2 (click to show)
SIT-2 (click to hide)
Title:
Zinc Chelation by a Small-Molecule Adjuvant Potentiates Meropenem Activity in Vivo against NDM-1-Producing Klebsiella pneumoniae
Reference:
ACS Infect. Dis., 2015, 1 (11), pp 533–543. Epub 8 May 2015.
Authors:
Falconer SB, Reid-Yu SA, King AM, Gehrke SS, Wang W, Britten JF, Coombes BK, Wright GD, and Brown ED.
Compounds:
SIT-1 (5677976), SIT-2 (5668345), SIT-3 (5675594), SIT-4 (5830995), SIT-Z5 (5833514), SIT-Z1 (5681294), SIT-Z2 {Not in our database}, SIT-Z3 {Not in our database}, SIT-Z4 {Not in our database}, SIT-Z5 (5833514), SIT-Z6 {Not in our database}, SIT-5 (5674906)